Smoked Cocaine Self-Administration is Decreased by Modafinil
نویسندگان
چکیده
منابع مشابه
Aminergic influences on intravenous cocaine self-administration by Rhesus monkeys.
WILSON, M. C. AND C. R. SCHUSTER. Aminergic influences on intravenous cocaine self-administration by rhesus monkeys. PHARMAC. BIOCHEM. BEHAV. 2(5) 563-571, 1974. Earlier observations have demonstrated that when allowed limited daily access to cocaine, monkeys self-administer approximately the same amount of cocaine dally. Treatment with neuroleptic agents increases the frequency of this behavio...
متن کاملCholinergic influence on intravenous cocaine self-administration by rhesus monkeys.
WILSON, M. C. AND C. R. SCHUSTER. 67rolhlergic influence on intravenous cocaine self-administration by rhesus monkeys. PHARMAC. BIOCHEM. BEIIAV. 1(6) 643-649, 1973.-The effects of intramuscular administration of atropine, methylatropine and physostigmine on intravenous cocaine self-administration in the rhesus monkey were ascertained. Atropine (0.5-2.0 mg/kg) increased cocaine intake, whereas m...
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There has been much interest in the relative importance of dopamine and serotonin transporters in the abuse-related-effects of cocaine. We tested the hypotheses that mice lacking the dopamine transporter (DAT(-/-)), the serotonin transporter (SERT(-/-)), or both (DAT(-/-)SERT(-/-)) exhibit decreased reinforcing effects of cocaine. We also assessed whether observed effects on self-administration...
متن کاملMaintained cocaine self-administration is determined by quantal responses: implications for the measurement of antagonist potency.
The change in frequency of cocaine self-administration as a function of the unit dose is widely assumed to represent a graded pharmacodynamic response. Alternatively, a pharmacological theory states that during maintained self-administration, a quantal response occurs at a minimum maintained cocaine concentration (satiety threshold). Rats self-administered cocaine at unit doses spanning an 8-fo...
متن کاملSmoked cocaine in socially-depressed areas
BACKGROUND The main objectives of this study are to describe the smoked cocaine user's profile in socially-depressed areas and their needs from a harm-reduction perspective, to investigate their use of smoking crack and compare the acute effects between injecting and smoking consumption. METHODS The study took place in SAPS, Barcelona, Spain. Two focus group sessions were undertaken with a to...
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ژورنال
عنوان ژورنال: Neuropsychopharmacology
سال: 2007
ISSN: 0893-133X,1740-634X
DOI: 10.1038/sj.npp.1301472